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In 1959, Saltztein collated a number of published reports with seven of his own cases and proposed the term drug-induced pseudolymphoma to describe this condition.[5] In the 1960s came reports of a syndrome similar to Saltztein's pseudolymphoma, but with rash and fever in addition to lymphadenopathy, and in 1988, the term anticonvulsant hypersensitivity syndrome was first used to label this specific entity.[6] These group of syndromes had been historically described by various names which include Dilantin hypersensitivity reaction, phenytoin/Dilantin syndrome, Kawasaki-like syndrome, mononucleosis-like syndrome, pseudolymphoma, febrile mucocutaneous syndrome, graft-versus-hostlike illness, Kawasaki-like illness, hypersensitivity mimicking infectious mononucleosis-like illness, multisystem hypersensitivity reaction, and drug-induced aseptic meningitis.[7,8] In 1998, the nomenclature was further confused by Sontheimer's suggestion of drug-induced delayed multiorgan hypersensitivity syndrome to describe this disorder.[4] At the same time, Bocquet et al coined the term, drug rash with eosinophilia and systemic symptoms, for those with systemic involvement, which subsequently got more acceptance.[9] A dermatosis is usual but not mandatory in DRESS
